Genetic variation in gonadal impairment in female survivors of childhood cancer: a PanCareLIFE study protocol

October 5, 2018

Survival rates following childhood cancer have increased to about 80% in developed countries thanks to improved risk stratification, as well as more effective treatment options. These options, however, can be tough, as 3 out of every 4 childhood cancer survivors develop at least one after effect, such as gonadal impairment.

Gonadal impairment is responsible for involuntary infertility in adults. Additionally, individuals affected may suffer early menopausal symptoms which can increase the likelihood of comorbidities such as cardiovascular disease.

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