Newly developed childhood cancer insights
December 27, 2018
One of the most common types of childhood cancers comes in the form of peripheral nervous system tumors. Although some of these cancers, such as neuroblastoma, may dissipate on their own, many continue to grow through intensive treatment. New findings from Berlin on the genetic factors underlying various tumor types have allowed physicians to develop methodical and adaptive treatments for these diseases.
Professor Dr. Johannes Schulte, one of the authors of this study details their findings stating, “the data they have produced has provided us with a precise means to classify neuroblastoma phenotypes.” The researchers involved in this study singled out mutations within the RAS and p53 signal transduction pathways typically responsible for a poor prognosis. These findings, however, also found instances of spontaneous tumor regression in patients with these mutations, providing hope